Impact of a methadone maintenance therapy pilot in Vietnam and its role in a scaled-up response

Table 2 Methadone and ART

	Follow-up periods						p value
	0–3 months	4–6 months	7–9 months	10–12 months	13–18 months	19–24 months
	(n = 930)	(n = 900)	(n = 871)	(n = 852)	(n = 802)	(n = 751)
Mean methadone doses at study visits, in ml (SE)
Hai Phong	9.6 (0.2)	9.9 (0.2)	9.5 (0.2)	9.5 (0.3)	9.4 (0.3)	9.6 (0.3)	0.248^a
HCMC	10.6 (0.2)	11.0 (0.3)	11.2 (0.3)	11.4 (0.3)	11.5 (0.4)	11.6 (0.4)	0.000^a
Total	10.1 (0.1)	10.4 (0.2)	10.4 (0.2)	10.4 (0.2)	10.4 (0.2)	10.6 (0.3)	0.000^a
Missed methadone dose for 1–2 days, in %
Hai Phong	19.5	23.6	30.7	41.1	48.4	47.7	0.000^a
HCMC	17.3	22.0	26.5	28.1	33.8	34.7	0.000^a
Total	18.4	22.8	28.6	34.6	41.3	41.4	0.000^a
Missed methadone doses for continuous 3–4 days, in %
Hai Phong	1.3	0.9	1.8	1.9	2.2	3.4	0.009^a
HCMC	0.6	0.9	1.4	0.7	1.0	4.1	0.000^a
Total	1.0	0.9	1.6	1.2	1.6	3.7	0.000^a
Missed methadone doses for a continuous 5 days or more, in %
Hai Phong	0.9	1.1	1.1	1.2	2.2	2.3	0.025^a
HCMC	1.3	0.9	1.4	0.9	3.3	4.1	0.000^a
Total	1.1	1.0	1.3	1.1	2.7	3.2	0.000^a
ARV treatment, in %
Hai Phong	14.2	12.9	15.1	14.0	16.3	16.0	0.202^a
HCMC	39.8	50.8	35.9	38.7	41.2	43.3	0.846^a
Total	27.2	31.9	25.5	26.3	28.4	29.2	0.827^a

ISSN: 1477-7517