Table 1 MEDLINE search strategy

1

"youth" OR "adolescen*" OR "young adult"

2,889,106

2

"adolescent"[MESH]

2,226,545

3

("youth" OR "adolescen*" OR "young adult") OR ("adolescent"[MESH])

2,889,106

4

"substance-related disorders"[MESH]

312,992

5

"harm reduction"[MESH]

4191

6

"harm reduction" OR "overdose prevention" OR "supervised consumption" OR "injection site" or "opioid agonist"

29,618

7

(("harm reduction" OR "overdose prevention" OR "supervised consumption" OR "injection site" or "opioid agonist") OR ("harm reduction"[MESH])) OR ("substance-related disorders"[MESH])

334,652

8

"barrier*" OR "constraint*" OR "limitation*" OR "concern*" OR "access*" OR "experienc*"

3,622,444

9

"British Columbia*" OR "Vancouver"

138,492

10

(((("youth" OR "adolescen*" OR "young adult") OR ("adolescent"[MESH])) AND ((("harm reduction" OR "overdose prevention" OR "supervised consumption" OR "injection site" or "opioid agonist") OR ("harm reduction"[MESH])) OR ("substance-related disorders"[MESH]))) AND ("barrier*" OR "constraint*" OR "limitation*" OR "concern*" OR "access*" OR "experienc*")) AND ("British Columbia*" OR "Vancouver")

390

11

(((("youth" OR "adolescen*" OR "young adult") OR ("adolescent"[MESH])) AND ((("harm reduction" OR "overdose prevention" OR "supervised consumption" OR "injection site" or "opioid agonist") OR ("harm reduction"[MESH])) OR ("substance-related disorders"[MESH]))) AND ("barrier*" OR "constraint*" OR "limitation*" OR "concern*" OR "access*" OR "experienc*")) AND ("British Columbia*" OR "Vancouver") Filters: from 2016 – 2023

251