Table 2 Systolic and diastolic blood pressure and heart rate during the run-in and each week of snus cessation presented as the mean and 95% confidence interval

Run-in

37

114.3 (110.2–118.4)

0 ref

72.5 (70.0–74.9)

0 ref

67.5 (64.5–70.5)

0 ref

Week 1

37

113.8 (109.7–117.9)

− 0.5 (− 2.0 to 1.1)

69.9 (67.3–72.5)

− 2.5 (− 3.8 to − 1.3)

61.7 (58.9–64.6)

− 5.7 (− 7.6 to − 3.9)

Week 2

36

115.8 (111.7–119.8)

1.1 (− 0.6 to 2.8)

71.3 (68.9–73.8)

− 1.6 (− 3.0 to − 0.1)

62.9 (60.1–65.7)

− 5.1 (− 6.9 to − 3.2)

Week 3

36

116.6 (112.5–120.8)

2.0 (− 0.1 to 4.1)

72.2 (69.6–74.8)

− 0.7 (− 2.3 to 1.0)

64.0 (61.2–66.8)

− 4.0 (− 5.8 to − 2.1)

Week 4

36

116.1 (111.7–120.5)

1.5 (− 0.6 to 3.5)

72.3 (69.7–74.8)

− 0.6 (− 2.3 to 1.1)

64.6 (61.8–67.4)

− 3.4 (− 5.4 to − 1.3)

Week 5

34

117.1 (112.5–121.6)

2.5 (0.3 to 4.7)

73.0 (70.3–75.7)

0.3 (− 1.2 to 1.8)

64.5 (61.7–67.4)

− 2.8 (− 4.3 to − 1.3)

Week 6

32

117.6 (113.1–122.0)

2.4 (0.3 to 4.6)

73.2 (70.4–76.0)

0.4 (− 1.4 to 2.2)

65.1 (61.9–68.4)

− 1.9 (− 3.4 to − 0.3)

Week 7

32

117.7 (113.2–122.1)

2.5 (0.3 to 4.8)

73.4 (70.6–76.2)

0.7 (− 1.1 to 2.5)

65.2 (61.9–68.6)

− 1.8 (− 3.2 to − 0.4)

Week 8

31

116.1 (112.5–119.6)

2.0 (− 0.1 to 4.0)

72.7 (70.2–75.3)

0.6 (− 1.4 to 2.5)

65.4 (61.7–69.1)

− 1.4 (− 3.3 to 0.5)

Week 9

31

115.5 (111.9–119.2)

2.3 (0.2 to 4.4)

71.9 (69.5–74.3)

0.4 (− 1.5 to 2.3)

64.3 (60.9–67.7)

− 1.6 (− 3.4 to 0.1)

Week 10

30

115.0 (111.3–118.7)

2.5 (0.4 to 4.5)

71.6 (69.4–73.9)

0.5 (− 1.3 to 2.2)

64.0 (60.8–67.2)

− 1.7 (− 3.4 to − 0.0)

Week 11

28

116.1 (112.5–119.7)

3.4 (1.2 to 5.7)

72.4 (69.9–74.8)

0.7 (− 1.3 to 2.7)

65.0 (61.2–68.8)

− 0.4 (− 2.1 to 1.3)

Week 12

29

115.8 (112.2–119.4)

3.7 (1.5 to 5.9)

72.0 (69.5–74.5)

0.6 (− 1.6 to 2.7)

65.2 (61.0–69.5)

− 0.6 (− 2.8 to 1.5)