Articles
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Citation: Harm Reduction Journal 2025 22:33
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Social support and HIV management among people who inject drugs: in-depth interviews in Delhi, India
People who inject drugs (PWID) experience a higher burden of HIV compared to general populations. Social support has been shown to improve disease management and combat stigma for PWID yet remains unexplored a...
Citation: Harm Reduction Journal 2025 22:32 -
Recent HIV testing and self-reported HIV prevalence among men who inject drugs in Afghanistan: a nationwide survey in 2019–2020
People who inject drugs (PWID) remain at high risk for HIV in many countries, including Afghanistan. Previous reports on HIV testing and prevalence in Afghanistan were published in 2012. This study assessed re...
Citation: Harm Reduction Journal 2025 22:31 -
Anonymous Opt-Out HIV and hepatitis C screening at a syringe services program in Florida
This paper outlines the implementation of opt-out HIV and Hepatitis C (HCV) screening at a syringe services program (SSP) in Florida, highlighting its effectiveness in reducing the transmission of these infect...
Citation: Harm Reduction Journal 2025 22:30 -
City-level drug policies in Portugal: the COVID-19 pandemic as an analyzer of harm reduction responsiveness in Porto and Lisbon
The COVID-19 pandemic health crisis and its potential implications for people who use drugs (PWUD) created permissive conditions toward social innovation and experimentation. Still, it also exposed gaps in har...
Citation: Harm Reduction Journal 2025 22:29 -
Is fentanyl in everything? Examining the unexpected occurrence of illicit opioids in British Columbia’s drug supply
Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and ...
Citation: Harm Reduction Journal 2025 22:28 -
Breaking the vicious cycle of delayed healthcare seeking for people who use drugs
People who use drugs (PWUD) are at increased mortality risk, yet they typically avoid healthcare settings due to stigma and shunning. Understanding the healthcare journey from the viewpoint of PWUD has been un...
Citation: Harm Reduction Journal 2025 22:27 -
Prevalence of HIV and Hepatitis C and access to opioid substitution treatment among people who inject drugs in three cities in Croatia: findings from the second wave of respondent-driven sampling surveys
The second wave of integrated bio-behavioural surveys was conducted among people who inject drugs (PWID) in the cities of Zagreb, Split, and Rijeka in Croatia to estimate the prevalence of HIV and hepatitis C ...
Citation: Harm Reduction Journal 2025 22:26 -
Perspectives of syringe services program operators in Michigan on their relationship with substance use treatment: a qualitative study
Substance use treatment (SUT) and harm reduction are often perceived as having distinct goals despite people who use drugs routinely having needs that encompass both services. The co-occurring SUT and harm red...
Citation: Harm Reduction Journal 2025 22:25 -
A qualitative study of benzodiazepine/z-drug and opioid co-use patterns and overdose risk
Co-use of benzodiazepines and/or ‘z-drugs’ along with opioids is linked to the rise in drug related deaths (DRD) in the UK. Understanding patterns of co-use could inform harm reduction strategies for reducing ...
Citation: Harm Reduction Journal 2025 22:24 -
For a renewed harm reduction model
In the early 1990s, the spread of HIV among heroin injectors prompted a shift in drug policy internationally, including in France. This led to the emergence of a new policy known as Harm Reduction (HR) and rel...
Citation: Harm Reduction Journal 2025 22:23 -
Mandatory verses voluntary self-tests for new online casino customers: effect on engagement, quality, gambling behavior and use of responsible gambling measures
To combat the public health concern that is problem gambling, gambling operators are increasingly being required by legislation to exercise a duty of care obligation, including the provision of Responsible Gam...
Citation: Harm Reduction Journal 2025 22:22 -
Prevalence and predictors of condom use among people who inject drugs in Georgia
People who inject drugs (PWID) are more likely to engage in unsafe sexual behavior placing them at high risk of acquiring HIV and other STIs. This study aims to assess the prevalence and predictors of inconsis...
Citation: Harm Reduction Journal 2025 22:21 -
Impact of UNODC/WHO S-O-S (stop-overdose-safely) training on opioid overdose knowledge and attitudes among people at high or low risk of opioid overdose in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine
Opioid overdose education and naloxone distribution (OEND) is an evidence-based strategy to reduce opioid overdose deaths in line with guidance provided by the World Health Organization (WHO) and United Nation...
Citation: Harm Reduction Journal 2025 22:20 -
Switching behavior and changes in smoking behavior by menthol cigarette preference and menthol heated tobacco product use among adults in the United States who smoke cigarettes: an actual use study
Heated tobacco products (HTPs) deliver nicotine with significantly lower toxicant exposure relative to combustible cigarettes. HTPs may serve as viable tobacco harm reduction options for adults who smoke but a...
Citation: Harm Reduction Journal 2025 22:19 -
Mechanisms of resilience and coping to intersectional HIV prevention and drug-use stigma among people who inject drugs in rural Appalachian Ohio
Intersectional stigma of drug-use and HIV hinders provision and utilization of HIV prevention services for people who inject drugs (PWID), particularly within rural US communities. Resilience and coping may be...
Citation: Harm Reduction Journal 2025 22:18 -
Utilization of drug checking services in Austria: a cross-sectional online survey
The use of psychoactive substances is a key public health issue due to its impact on mental, physical, and social health. Integrated drug checking is a well-known harm reduction and addiction prevention measur...
Citation: Harm Reduction Journal 2025 22:17 -
Addressing viral hepatitis C reinfections in a low-threshold programme for people who inject drugs in Slovenia
Hepatitis C virus (HCV) infection remains a public health threat. Although therapy with direct-acting antivirals made its elimination possible, major challenges remain in treating vulnerable populations, such ...
Citation: Harm Reduction Journal 2025 22:16 -
Limit-setting in online gambling: a comparative policy review of European approaches
Online gambling products involve a heightened risk of harm, but there are some possibilities to prevent and reduce these harms. Notably, mandatory identification in online gambling environments allows for a ra...
Citation: Harm Reduction Journal 2025 22:15 -
Opioid consumption frequency and its associations with potential life problems during opioid agonist treatment in individuals with prescription-type opioid use disorder: exploratory results from the OPTIMA Study
Traditional treatment approaches for prescription-type opioid use disorder (POUD), centered on abstinence, have limitations and hinder the development of interventions that meet the needs of people with POUD. ...
Citation: Harm Reduction Journal 2025 22:14 -
Barriers to uptake of harm reduction techniques for GBMSM who use drugs in night-clubs and sex-on-premises venues in London and the Southeast: a mixed-methods, qualitative study
Drug-related harm is a significant public health concern in the UK, particularly among underserved groups such as gay, bisexual, and other men who have sex with men (GBMSM). This study explores the role of nig...
Citation: Harm Reduction Journal 2025 22:13 -
Assessment of knowledge and behaviors of an opioid overdose education and naloxone distribution program during the coronavirus disease 2019 pandemic
The state of Louisiana ranked 4th in the US for per capita overdose rates as 56 out of 100,000 persons died due to overdose and 1,300 of those deaths involved opioids. Opioid involved deaths increased 131% bet...
Citation: Harm Reduction Journal 2025 22:12 -
Developing a comprehensive inventory to define harm reduction housing
The City of Boston has faced unprecedented challenges with substance use amidst changes to the illicit drug supply and increased visibility of homelessness. Among its responses, Boston developed six low thresh...
Citation: Harm Reduction Journal 2025 22:11 -
Future destinations: how people cured of hepatitis C using direct acting antiviral drugs progress in a new HCV-free world. A thematic analysis
The introduction of Direct-Acting Antivirals (DAAs) transformed Hepatitis C (HCV) treatment, despite this uptake of DAAs remains lower than required to meet the WHO Sustainable Development Goal (3.3). Treatmen...
Citation: Harm Reduction Journal 2025 22:10 -
Reducing medical cannabis use risk among Veterans: A descriptive study
Canadian Veterans experiencing chronic pain report concerns about accessing accurate information on the risks associated with medical cannabis (MC) use. The Lower Risk Cannabis Use Guidelines (LRCUG) were deve...
Citation: Harm Reduction Journal 2025 22:9 -
Opioid-related harms and experiences of care among people in justice settings in New South Wales, Australia: evidence from the National Ambulance Surveillance System
People in justice settings experience higher rates of psychiatric morbidity, including alcohol and drug use disorders, compared with the general population. However, our understanding of opioid-related harms i...
Citation: Harm Reduction Journal 2025 22:8 -
An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine
In the United States, complete abstinence persists as the standard for demonstrating recovery success from substance use disorders (SUDs), apart from alcohol use disorder (AUD). Although the FDA has recently i...
Citation: Harm Reduction Journal 2025 22:7 -
The implementation of safer drug consumption facilities in Scotland: a mixed methods needs assessment and feasibility study for the city of Edinburgh
Scotland currently has amongst the highest rates of drug-related deaths in Europe, leading to increased advocacy for safer drug consumption facilities (SDCFs) to be piloted in the country. In response to conce...
Citation: Harm Reduction Journal 2025 22:6 -
Mind the G(ap): bridging prevention needs and approaches for GHB/GBL users and their social environment
Gamma-hydroxybutyrate (GHB) and its precursors gamma-butyrolactone (GBL) and 1,4-butanediol (BD) have become a significant concern due to the increase in their recreational use and the high risks associated wi...
Citation: Harm Reduction Journal 2025 22:5 -
Facilitators and Barriers to adherence to antiretroviral therapy among incarcerated people living with HIV in Iran: insights from a qualitative study
Ensuring consistent adherence to antiretroviral therapy (ART) is crucial for effective HIV treatment and achieving viral suppression. Within prisons, the prevalence of HIV is notably high, and incarcerated ind...
Citation: Harm Reduction Journal 2025 22:4 -
The impact of Covid-19 on harm reduction policies in Iran: an interrupted time series analysis
The global emergence of the Covid-19 pandemic in 2019 posed unprecedented challenges to healthcare systems, disrupting routine services and necessitating swift adaptations. Harm reduction programs, vital for a...
Citation: Harm Reduction Journal 2025 22:3 -
Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico
Xylazine is a α2-adrenergic receptor agonist, used for sedation in veterinary contexts. Although it is increasingly found in overdose deaths across North America, the clinical management of xylazine-involved o...
Citation: Harm Reduction Journal 2025 22:2 -
Channelling and taxation in European online gambling markets: evolution and policy implications
Taxation can be used to direct consumption and provision of harmful commodities. Prior research on gambling taxation has nevertheless been inconclusive on whether this can also apply to gambling. In gambling p...
Citation: Harm Reduction Journal 2025 22:1 -
“It’s a delicate balance”: clinicians’ experiences of providing heroin-assisted treatment
Little attention has been paid to the experiences of clinicians and health personnel who provide heroin-assisted treatment (HAT). This study provides the first empirical findings about the clinicians’ experien...
Citation: Harm Reduction Journal 2024 21:230 -
Oral health risks in adults who use electronic nicotine delivery systems and oral nicotine pouches: a critical review of the literature and qualitative synthesis of the available evidence
Use of combustible cigarettes (CCs) and smokeless oral tobacco products are well documented risk factors for a variety of oral diseases. However, the potential oral health risks of using recently introduced (s...
Citation: Harm Reduction Journal 2024 21:229 -
Identifying the facilitators of Iran’s alcoholic beverage black market and presenting solutions for harm reduction: a qualitative document analysis
Despite Iran’s prohibition politics regarding alcoholic beverages consumption, marketing, and trading, there is a flourishing black market. Often, alcohol producers on this black market do not adhere alcohol p...
Citation: Harm Reduction Journal 2024 21:228 -
Assessing healthcare cost changes associated with transitioning away from cigarette smoking using healthcare claims data: an exploratory study among adult male patients with COPD
The assessment of potential health effects of switching from cigarette smoking to non-combustible tobacco products has important implications for public health and regulatory decisions. Robust epidemiological ...
Citation: Harm Reduction Journal 2024 21:227 -
The theory of preloading: A cognitive-behavioural motivational model
Preloading of alcohol and/or drugs before an event has been examined in the research literature for the past two decades. Despite the considerable interest and scrutiny on the behaviour, there are limited, if ...
Citation: Harm Reduction Journal 2024 21:226 -
Exploring perceived quality of life in long-term methadone-dependent patients: a qualitative study
Considering opioid use disorder (OUD) as one of the major global concerns, methadone maintenance treatment (MMT) has been documented the core treatment for such dependence in the affected individuals. With reg...
Citation: Harm Reduction Journal 2024 21:225 -
Relational anonymity in reducing the harms of illicit drug use: accounts of users of dark web- and street-based services in Finland
Protecting individual anonymity is a common practice in harm reduction (HR), as it can mitigate the fears that may prevent people from accessing services. Protecting anonymity usually means applying for servic...
Citation: Harm Reduction Journal 2024 21:224 -
Developing an ethical framework for the recruitment of people who inject drugs experiencing incarceration in HIV prevention research: a qualitative study
HIV disproportionately impacts people who experience incarceration. Incarceration represents an opportunity to engage in HIV prevention care for individuals who often experience a number of barriers accessing ...
Citation: Harm Reduction Journal 2024 21:223 -
Progress and challenges in the elimination of hepatitis C among people who inject drugs in Germany: results of a pilot study for a national monitoring system, 10 years after the first data collection
People who inject drugs (PWID) are at high risk of blood-borne infections, and injection drug use contributes significantly to hepatitis C virus (HCV) transmission. The WHO has therefore set targets of reducin...
Citation: Harm Reduction Journal 2024 21:222 -
Practical solutions to resolve social barriers to hepatitis C treatment initiation among people who inject drugs: a qualitative study
We aimed to identify motivators for people who inject drugs to pursue treatment for hepatitis C virus (HCV) infection and uncover opportunities that could make treatment more appealing.
Citation: Harm Reduction Journal 2024 21:221 -
Understanding the financial barriers to treatment among individuals with opioid use disorder: a focus group study
Despite the established effectiveness and relatively widespread availability of Medications for Opioid Use Disorder, individuals seeking treatment frequently encounter various structural and social barriers, i...
Citation: Harm Reduction Journal 2024 21:220 -
Harm reduction and its monitoring in Europe, from EMCDDA to EUDA
Harm Reduction, conceptualized by Russell Newcombe in the late 1980s, has revolutionized how drug use, individuals who use drugs, and drug policies are understood globally. Emerging from the HIV/AIDS crisis, H...
Citation: Harm Reduction Journal 2024 21:219 -
Door-to-door overdose harm reduction: an Illinois case study
Harm reduction for people who use drugs (PWUD) is an established evidence-based practice that encompasses a wide variety of services, delivery formats, and settings and has been named a priority in US drug pol...
Citation: Harm Reduction Journal 2024 21:218 -
Challenges for the implementation of injectable opioid agonist treatment: a scoping review
Injectable opioid agonist treatment (iOAT) is a valuable, patient-centred, evidence based intervention. However, limited information exists on contextual factors that may support or hinder iOAT implementation ...
Citation: Harm Reduction Journal 2024 21:217 -
Exploring drug consumption rooms as ‘inclusion health interventions’: policy implications for Europe
People who use drugs are among the most socially excluded groups in Europe. Qualitative research on Drug Consumption Rooms (DCRs) has reported various benefits to clients, including increased feelings of well-...
Citation: Harm Reduction Journal 2024 21:216 -
People who use drugs and the right to health
Support for a human rights framework for drug policy has been growing for some years. This year, the UNODC published a chapter in the World Drug Report focussed on the right to health. In this paper, we draw a...
Citation: Harm Reduction Journal 2024 21:215 -
Correction: Implementation of a community-based LC-UV drug checking service: promising preliminary findings on feasibility and validity
Citation: Harm Reduction Journal 2024 21:213